TriangleLifileucel (LN-144/LN-145) (NCT05607095)
Lifileucel (LN-144/LN-145) trial for Uveal Melanoma (NCT05607095). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for metastatic uveal melanoma, and for certain advanced sarcomas: undifferentiated pleomorphic sarcoma, dedifferentiated liposarcoma and angiosarcoma, in adults.
The idea: use a patient's own immune cells. Surgeons remove tumor tissue, and tumor infiltrating lymphocytes, a type of white blood cell, are grown from it. Melanoma and sarcoma patients are treated in separate groups. Iovance Biotherapeutics is listed as a collaborator.
This pilot plans 40 patients, and safety is the main measure. At Memorial Sloan Kettering Cancer Center in New York, Lauren Banks leads it.
Public record; not medical advice.
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