TriangleLifileucel (LN-144/LN-145) (NCT05607095)
Lifileucel (LN-144/LN-145) trial for Uveal Melanoma (NCT05607095). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
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This trial is for metastatic uveal melanoma, and for certain advanced sarcomas: undifferentiated pleomorphic sarcoma, dedifferentiated liposarcoma and angiosarcoma, in adults.
The idea: use a patient's own immune cells. Surgeons remove tumor tissue, and tumor infiltrating lymphocytes, a type of white blood cell, are grown from it. Melanoma and sarcoma patients are treated in separate groups. Iovance Biotherapeutics is listed as a collaborator.
This pilot plans 40 patients, and safety is the main measure. At Memorial Sloan Kettering Cancer Center in New York, Lauren Banks leads it.
Public record; not medical advice.
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