TriangleCAR.70/IL15-transduced CB-NK cells (NCT05092451)
CAR.70/IL15-transduced CB-NK cells trial for B-Cell Lymphoma (NCT05092451). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
Lo que dice el vídeo
Lee la transcripción
CAR T cells have cured some blood cancers. But they must be built from each patient's own blood, over weeks, and a relapsed patient may not have weeks.
The idea: build the cells in advance, from umbilical cord blood, so they wait in the freezer.
Natural killer cells from donated cord blood are given a receptor for CD70, a protein on many leukemias, lymphomas, and myelomas but few healthy cells. They also carry a gene for interleukin-15, a survival signal, so they persist. In myeloma models, they kept working after the usual target, BCMA, disappeared.
MD Anderson, with David Marin, gives one dose after chemotherapy makes room, to patients from age twelve whose cancer carries CD70. Safety first. Public record; not medical advice.
¿Ya estás en un ensayo?
Se convierte en un proyecto que hay que manejar: citas, estudios de imagen, análisis, efectos secundarios y papeleo. Triangle lo mantiene organizado en un solo lugar, para ti o para quien te ayuda.
Organizar mi ensayoPrueba gratuita de 7 días, después $9 al mes. Cancela cuando quieras.
Cómo funcionan estos ensayos: qué es de verdad la fase 1 · preguntas frecuentes No es evidencia clínica.