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Cognitive Sparing Brain Stereotactic… (NCT04343157)

UCSD Image-Guided Cognitive-Sparing Radiosurgery for Intracranial Lesions: a one-minute explainerNCT043431571 min

Cognitive Sparing Brain Stereotactic Radiosurgery (SRS) trial for Brain Metastases, Adult (NCT04343157). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults with limited brain metastases, meningioma or a cerebral arteriovenous malformation suitable for stereotactic radiosurgery. Prior whole-brain radiation and lesions invading protected brain regions are excluded. Some eligible conditions are noncancerous.

The idea: use advanced MRI mapping to direct radiation while reducing dose to memory-related brain structures. Everyone receives the planning approach; cognitive results are compared with earlier patients. MRI and thinking tests track changes after treatment.

This phase 2 study plans 90 patients. UC San Diego’s Jona Hattangadi-Gluth leads it at Moores, the sole recruiting US site.

Public record; not medical advice.

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