TriangleCAR.70 NK Cells (NCT07444632)
CAR.70 NK Cells trial for Relapsed or Refractory Lymphomas and B-ALL (NCT07444632). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with lymphomas or B cell acute lymphoblastic leukemia that have come back or not responded to treatment.
The idea: natural killer cells from donated umbilical cord blood are engineered with a CAR that targets CD70, given interleukin 15 to help them last, and edited so they ignore a suppressive signal called TGF beta. After short chemotherapy, the cells are given by vein.
The study looks at safety.
This phase 1 study plans 60 patients. At MD Anderson Cancer Center in Houston, Yago Nieto leads it.
Public record; not medical advice.
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