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STARLITE (NCT06428045)

How STARLITE worksNCT064280451 min

STARLITE trial for High Grade Glioma (NCT06428045). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for newly diagnosed high grade glioma, a brain tumor, that cannot be removed surgically, in adults.

The idea: combine heat and antiretroviral drugs. After a needle biopsy, MRI guided laser therapy heats the tumor. A week later, patients start combination antiretroviral therapy, with the ritonavir dose raised or lowered to find the best dose.

This phase 1 study plans 24 patients and first looks at dose limiting toxicity. At the University of Miami, Ashish Shah and Macarena De La Fuente lead it.

Public record; not medical advice.

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How these trials work: what Phase 1 actually is · common questions Not clinical evidence.