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Pembrolizumab + Single-Agent… (NCT04297605)

How Pembrolizumab + Single-Agent Chemotherapy worksNCT042976051 min

Pembrolizumab + Single-Agent Chemotherapy trial for Locally Advanced or Metastatic Non-Small Cell Lung Cancer (ECOG 2) (NCT04297605). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

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This trial is for locally advanced or metastatic non-small cell lung cancer, in adults whose daily activity is limited, called performance status 2.

The idea: pair immunotherapy with a single chemotherapy drug. Pembrolizumab is given with either pemetrexed or nab-paclitaxel, every 21 days, as first treatment. The study enrolls patients with stage three C or stage four disease.

This pilot phase 1 study asks whether the combination is tolerable, and plans 60 patients. At the University of Rochester in New York, Megan Baumgart leads it.

Public record; not medical advice.

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How these trials work: what Phase 1 actually is · common questions Not clinical evidence.