TriangleCD19-CAR T Cells for CNS Lymphoma (NCT05625594)
CD19-CAR T Cells for CNS Lymphoma trial for Central Nervous System Lymphoma (NCT05625594). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for lymphoma in the central nervous system, either lymphoma that began there or lymphoma that returned only in the brain and spinal fluid.
The idea: deliver CAR T cells right where the lymphoma is. The patient's T cells are engineered with a receptor for CD19, a protein on the lymphoma cells, and grown in the lab. Instead of a vein, the cells are infused into the brain's fluid-filled spaces through a surgically placed catheter.
The study asks about safety, feasibility, and the best dose. At City of Hope in California, Tanya Siddiqi leads it.
Public record; not medical advice.
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