TriangleCD19-CAR T Cells for CNS Lymphoma (NCT05625594)
CD19-CAR T Cells for CNS Lymphoma trial for Central Nervous System Lymphoma (NCT05625594). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
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This trial is for lymphoma in the central nervous system, either lymphoma that began there or lymphoma that returned only in the brain and spinal fluid.
The idea: deliver CAR T cells right where the lymphoma is. The patient's T cells are engineered with a receptor for CD19, a protein on the lymphoma cells, and grown in the lab. Instead of a vein, the cells are infused into the brain's fluid-filled spaces through a surgically placed catheter.
The study asks about safety, feasibility, and the best dose. At City of Hope in California, Tanya Siddiqi leads it.
Public record; not medical advice.
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