Triangle15.GPC3-CAR T cells (NCT06815432)
15.GPC3-CAR T cells trial for Glioblastoma Multiforme of Brain (NCT06815432). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
Glioblastoma often returns after surgery, radiation, and chemotherapy. This study is for glioblastoma that has come back and carries a protein called GPC3.
The idea: give a patient's own immune cells a new target. T cells are taken from the blood, and genes are added so they recognize GPC3 and keep growing. The cells also carry a safety switch, so a drug can remove them if side effects appear.
During a surgery that is already planned, the cells are placed directly into the tumor area, one time. At Baylor St. Luke's in Houston, Ganesh Rao leads this early study. The first question is safety and dose.
Public record; not medical advice.
Already in a trial?
It turns into a project to manage: visits, scans, labs, side effects and paperwork. Triangle keeps it organized in one place for you or for whoever's helping.
Organize my trial7-day free trial, then $9 a month. Cancel anytime.
How these trials work: what Phase 1 actually is · common questions Not clinical evidence.