TriangleChemoimmunotherapy + SFRT and… (NCT06546969)
Chemoimmunotherapy + SFRT and Hyperthermia trial for Advanced Biliary Tract Cancer (NCT06546969). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
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This trial is for adults with advanced biliary tract cancer, including cholangiocarcinoma, who do not qualify for surgery.
The idea: add two treatments to standard chemoimmunotherapy with gemcitabine, cisplatin and durvalumab. One tumor gets a single dose of spatially fractionated radiation, then two sessions of deep hyperthermia, which heats the tumor.
This phase 1 study plans 15 patients and measures serious side effects and whether heating reaches its target. At the University of Maryland in Baltimore, Jason Molitoris leads it.
Public record; not medical advice.
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