TriangleCARLOTTA01 (NCT05836896)
CARLOTTA01 trial for Neoplasms (NCT05836896). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
Lo que dice el vídeo
Lee la transcripción
Multiple myeloma comes back, again and again, until the standard drug classes are exhausted. CAR T cells aimed at BCMA, a marker on myeloma cells, are approved and effective, but relapses follow.
The idea: an academic BCMA CAR T, built with a tighter grip on its target.
At the University Hospital in Dresden, a patient's own T cells receive a high-affinity receptor for BCMA, designed to bind the marker more firmly than earlier constructs. After conditioning chemotherapy, the cells are returned in a single infusion, at one of four rising dose levels.
CARLOTTA-01 is a first safety study, for myeloma after at least two prior lines and for some relapsed large B-cell lymphomas. Martin Wermke leads it. Public record; not medical advice.
¿Ya estás en un ensayo?
Se convierte en un proyecto que hay que manejar: citas, estudios de imagen, análisis, efectos secundarios y papeleo. Triangle lo mantiene organizado en un solo lugar, para ti o para quien te ayuda.
Organizar mi ensayoPrueba gratuita de 7 días, después $9 al mes. Cancela cuando quieras.
Cómo funcionan estos ensayos: qué es de verdad la fase 1 · preguntas frecuentes No es evidencia clínica.