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← Childhood Cancer Genomics (PDQ®)

HEALTH PROFESSIONAL · SOURCE READING

Molecular features of pediatric-type high-grade gliomas

Source: Childhood Cancer Genomics (PDQ®)–Health Professional Version, National Cancer Institute.

Source updated: April 30, 2025 · Captured 2026-09-09.

Selected source text with whitespace normalised. This Triangle page is not an NCI PDQ summary. Independent clinical review is pending.

Context: Central Nervous System Tumors / Astrocytomas, Other Gliomas, and Glioneuronal/Neuronal Tumors

Pediatric high-grade gliomas are biologically distinct from those arising in adults.[5,33-35]

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Subgroups identified using DNA methylation patterns →Other variants →High-grade gliomas in infants →Secondary high-grade glioma →

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Preserved source evidence · Independent clinical review pending · Not medical advice