FDA approved sevabertinib, a kinase inhibitor, for adult patients with locally advanced or metastatic non-squamous non-small cell lung cancer whose tumors have HER2 tyrosine kinase domain activating mutations, as detected by an FDA-authorized test.
FDA approved camizestrant, an estrogen receptor antagonist, in combination with a CDK4/6 inhibitor for adults with hormone receptor -positive, human epidermal growth factor receptor 2 -negative locally advanced or metastatic breast cancer upon detection of estrogen receptor-1 mutation during aromatase inhibitor and CDK4/6 inhibitor therapy, based on an FDA-authorized test.
FDA approved daraxonrasib, an inhibitor of the RAS GTPase family, for adults with metastatic pancreatic adenocarcinoma who have received at least one prior systemic therapy or who are not candidates for multiagent systemic therapy.
FDA approved iberdomide in combination with daratumumab and hyaluronidase-fihj and dexamethasone for adults with multiple myeloma who have received at least one prior line of therapy including a proteasome inhibitor and an immunomodulatory agent.
FDA approved vusolimogene oderparepvec-wtpg, a genetically modified oncolytic viral therapy, in combination with nivolumab for the treatment of adult patients with unresectable advanced cutaneous melanoma who experienced disease progression on a programmed death receptor-1 -blocking antibody-based regimen.
FDA approved lutetium Lu 177 vipivotide tetraxetan in combination with androgen receptor pathway inhibitor therapy for adults with prostate-specific membrane antigen -positive metastatic androgen pathway modulation-naïve or-sensitive prostate cancer .
Search stays in your browser. A newer date does not mean stronger evidence or a better treatment.
About this research feed
Papers are citations captured from NCI source reading, not a comprehensive literature search. Titles and bibliographic metadata are preserved; abstracts and full texts are not included. Corrections, retractions and concerns present in the snapshot are flagged; missing flags do not establish that a paper is unaffected.
Trial entries use the date results were first posted, not the date a registry record was last updated. Dates marked estimated by the source stay explicitly labelled. An administrative update is not presented as new findings. Cited trials and condition-search discoveries are labelled separately; this is not a representative sample of all trials.
Papers use the supplied online-publication date when available, otherwise the supplied publication date. Partial dates stay partial and sort after precisely dated entries in the same month or year. An FDA notice is not confirmation of current approved use or a treatment recommendation. Safety notices are distinct from approvals.
0 records without a usable event date and 0 with dates after the release cutoff are not placed in the dated feed. The original records remain in the source library.
Preserved source evidence · Independent clinical review pending · Not medical advice