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DISEASE & TREATMENT SETTING

Cervical Cancer

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

Cervical Cancer

Source population
Not part of this definition
Disease extent
Not part of this definition
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
      derivation status
      unresolved
      derivation note
      Derived from NCI topic(s): Cervical Cancer; Cervical Cancer Treatment During Pregnancy. Strongest NCIt resolution: ambiguous. Entity-level scope; stage, biomarker and treatment line are not yet part of this definition.
      source wording
      Source null
      20 more-specific settings

      Study evidence for this setting

      54 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

      NCT00025233 · Source cited / selected · Scope: narrower

      Bevacizumab in Treating Patients With Persistent or Recurrent Cancer of the Cervix

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00064077 · Source cited / selected · Scope: narrower

      Comparison of Four Combination Chemotherapy Regimens Using Cisplatin in Treating Patients With Stage IVB, Recurrent, or Persistent Cancer of the Cervix

      6 outcome links · 4 safety-group records · 3 quality-of-life measures

      →

      NCT00092521 · Registry condition search · Scope: narrower

      Cervical Intraepithelial Neoplasm (CIN)-Warts Efficacy Trial in Women (Gardasil)(V501-013)(COMPLETED)

      2 outcome links · 4 safety-group records · 0 quality-of-life measures

      →

      NCT00331760 · Source cited / selected · Scope: narrower

      Intensity-Modulated Radiation Therapy to the Pelvis With or Without Chemotherapy in Treating Patients With Endometrial Cancer or Cervical Cancer That Has Been Removed By Surgery

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00365508 · Registry condition search · Scope: narrower

      Counseling and Nicotine Replacement Therapy in Helping Adult Smokers Quit Smoking

      2 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00381888 · Registry condition search · Scope: narrower

      Fondaparinux in Preventing Blood Clots in Patients Undergoing Surgery for Gynecologic Cancer

      2 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00534001 · Registry condition search · Scope: narrower

      Bupropion in Helping Adults Stop Smoking

      2 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00543543 · Registry condition search · Scope: narrower

      Broad Spectrum HPV (Human Papillomavirus) Vaccine Study in 16-to 26-Year-Old Women (V503-001)

      6 outcome links · 6 safety-group records · 0 quality-of-life measures

      →

      NCT00545792 · Registry condition search · Scope: narrower

      Safety Study Of Avastin And Pelvic Radiation In Women With Recurrent Gynecological Cancers

      2 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00577317 · Registry condition search · Scope: narrower

      Flexitouch® Home Maintenance Therapy or Standard Home Maintenance Therapy in Treating Patients With Lower-Extremity Lymphedema Caused by Treatment for Cervical Cancer, Vulvar Cance

      6 outcome links · 2 safety-group records · 1 quality-of-life measures

      →

      NCT00587964 · Registry condition search · Scope: narrower

      Phase II Trial of Stereotactic Radiosurgery Boost Following Surgical Resection for Brain Metastases

      1 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT00666978 · Registry condition search · Scope: narrower

      Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking

      4 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT00790569 · Registry condition search · Scope: narrower

      Varenicline or Nicotine Patch and Nicotine Gum in Helping Smokers in a Methadone Treatment Program Stop Smoking

      6 outcome links · 3 safety-group records · 0 quality-of-life measures

      →

      NCT00803062 · Source cited / selected · Scope: narrower

      Paclitaxel and Cisplatin or Topotecan With or Without Bevacizumab in Treating Patients With Stage IVB, Recurrent, or Persistent Cervical Cancer

      6 outcome links · 4 safety-group records · 1 quality-of-life measures

      →

      NCT00851643 · Registry condition search · Scope: narrower

      Broad Spectrum HPV Vaccine Dose Escalation Study (V502-002)

      4 outcome links · 5 safety-group records · 0 quality-of-life measures

      →

      NCT00941070 · Registry condition search · Scope: narrower

      Triapine, Cisplatin, and Radiation Therapy in Treating Patients With Cervical Cancer or Vaginal Cancer

      6 outcome links · 1 safety-group records · 1 quality-of-life measures

      →

      NCT00943722 · Registry condition search · Scope: narrower

      A Study of V503 (A Multivalent Human Papillomavirus [HPV] L1 Virus-Like Particle [VLP] Vaccine) in Preadolescents and Adolescents (V503-002)

      6 outcome links · 9 safety-group records · 0 quality-of-life measures

      →

      NCT00957424 · Registry condition search · Scope: narrower

      Acceptability of Less Harmful Alternatives to Cigarettes

      4 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT01047345 · Registry condition search · Scope: narrower

      A Study of V503, a 9-valent Human Papillomavirus (9vHPV) Vaccine in Females 12-26 Years of Age Who Have Previously Received GARDASIL™ (V503-006)

      6 outcome links · 3 safety-group records · 0 quality-of-life measures

      →

      NCT01079832 · Registry condition search · Scope: narrower

      Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies

      5 outcome links · 1 safety-group records · 1 quality-of-life measures

      →

      Indication-specific source history

      Dated source events, not confirmation of current approval for every use of a drug.

      2018-06-12 · Keytruda (pembrolizumab) · accelerated approval
      release id
      clinical-indications-draft-1
      disease state id
      ds-cervical-cancer
      event id
      fda-b0651a0c19a6d573
      event date
      2018-06-12
      event kind
      accelerated-approval
      drug or regimen
      Keytruda (pembrolizumab)
      source indication text
      Treatment of patients with recurrent or metastatic cervical cancer with disease progression on or after chemotherapy whose tumors express PD-L1 (CPS >/=1) as determined by an FDA approved test
      match phrase
      cervical cancer
      match status
      candidate
      status category
      verified_clinical_benefit
      has date discrepancy
      0
      source collection
      fda-status-row
      source key
      fda-aa-2a65b4873420497564e0
      source url
      https://www.fda.gov/drugs/resources-information-approved-drugs/verified-clinical-benefit-cancer-accelerated-approvals
      curation status
      draft
      reviewed by
      Source null
      reviewed at
      Source null
      created at
      2026-09-10T00:00:00Z
      Original event source →
      2021-09-20 · Tivdak (tisotumab vedotin-tftv) · accelerated approval
      release id
      clinical-indications-draft-1
      disease state id
      ds-cervical-cancer
      event id
      fda-6c67bc46de8bcf18
      event date
      2021-09-20
      event kind
      accelerated-approval
      drug or regimen
      Tivdak (tisotumab vedotin-tftv)
      source indication text
      Treatment of adult patients with recurrent or metastatic cervical cancer with disease progression on or after chemotherapy
      match phrase
      cervical cancer
      match status
      candidate
      status category
      verified_clinical_benefit
      has date discrepancy
      0
      source collection
      fda-status-row
      source key
      fda-aa-362e4da2080143274786
      source url
      https://www.fda.gov/drugs/resources-information-approved-drugs/verified-clinical-benefit-cancer-accelerated-approvals
      curation status
      draft
      reviewed by
      Source null
      reviewed at
      Source null
      created at
      2026-09-10T00:00:00Z
      Original event source →
      2021-10-13 · Keytruda (pembrolizumab) · traditional approval
      release id
      clinical-indications-draft-1
      disease state id
      ds-cervical-cancer
      event id
      fda-330ea9c942f7cd84
      event date
      2021-10-13
      event kind
      traditional-approval
      drug or regimen
      Keytruda (pembrolizumab)
      source indication text
      Treatment of patients with recurrent or metastatic cervical cancer with disease progression on or after chemotherapy whose tumors express PD-L1 (CPS >/=1) as determined by an FDA approved test
      match phrase
      cervical cancer
      match status
      candidate
      status category
      verified_clinical_benefit
      has date discrepancy
      0
      source collection
      fda-status-row
      source key
      fda-aa-2a65b4873420497564e0
      source url
      https://www.fda.gov/drugs/resources-information-approved-drugs/verified-clinical-benefit-cancer-accelerated-approvals
      curation status
      draft
      reviewed by
      Source null
      reviewed at
      Source null
      created at
      2026-09-10T00:00:00Z
      Original event source →
      2024-04-29 · Tivdak (tisotumab vedotin-tftv) · traditional approval
      release id
      clinical-indications-draft-1
      disease state id
      ds-cervical-cancer
      event id
      fda-63e6ccc5f391819c
      event date
      2024-04-29
      event kind
      traditional-approval
      drug or regimen
      Tivdak (tisotumab vedotin-tftv)
      source indication text
      Treatment of adult patients with recurrent or metastatic cervical cancer with disease progression on or after chemotherapy
      match phrase
      cervical cancer
      match status
      candidate
      status category
      verified_clinical_benefit
      has date discrepancy
      0
      source collection
      fda-status-row
      source key
      fda-aa-362e4da2080143274786
      source url
      https://www.fda.gov/drugs/resources-information-approved-drugs/verified-clinical-benefit-cancer-accelerated-approvals
      curation status
      draft
      reviewed by
      Source null
      reviewed at
      Source null
      created at
      2026-09-10T00:00:00Z
      Original event source →
      Source relationships and population-mapping limitations
      bindings
      1. release id
        clinical-indications-draft-1
        disease state id
        ds-cervical-cancer
        binding id
        ncit-C9039
        source collection
        ncit-concept
        source key
        C9039
        source excerpt
        Source null
        match status
        ambiguous
        match note
        Resolution status: ambiguous.
        recorded at
        2026-09-10T00:00:00Z
      2. release id
        clinical-indications-draft-1
        disease state id
        ds-cervical-cancer
        binding id
        ncit-C9311
        source collection
        ncit-concept
        source key
        C9311
        source excerpt
        Source null
        match status
        ambiguous
        match note
        Resolution status: ambiguous.
        recorded at
        2026-09-10T00:00:00Z
      mappings

        Download this complete draft source relationship record →

        Preserved source evidence · Not medical advice