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DISEASE & TREATMENT SETTING

ALYMSYS: metastatic cervical cancer

Source-derived catalogue. This is not a treatment recommendation or a personalised trial match.

Exact scope

1.5 Persistent, Recurrent, or Metastatic Cervical Cancer Alymsys, in combination with paclitaxel and cisplatin or paclitaxel and topotecan, is indicated for the treatment of patients with persistent, recurrent, or metastatic cervical cancer.

Broader topic: Cervical Cancer

Source population
Not part of this definition
Disease extent
metastatic
Treatment line
Not part of this definition
Stage
Not part of this definition
Resectability
Not part of this definition
Biomarkers, prior therapy and derivation
molecular
    prior therapy
      derivation status
      source-attested
      derivation note
      Scoped from the FDA approved indication for ALYMSYS (product label). Only dimensions stated in that wording are part of this definition.
      source wording
      1.5 Persistent, Recurrent, or Metastatic Cervical Cancer Alymsys, in combination with paclitaxel and cisplatin or paclitaxel and topotecan, is indicated for the treatment of patients with persistent, recurrent, or metastatic cervical cancer.

      Study evidence for this setting

      15 linked studies · Applicability is a draft source assessment, not a determination of your eligibility.

      NCT00577317 · Registry condition search · Scope: unclear

      Flexitouch® Home Maintenance Therapy or Standard Home Maintenance Therapy in Treating Patients With Lower-Extremity Lymphedema Caused by Treatment for Cervical Cancer, Vulvar Cance

      6 outcome links · 2 safety-group records · 1 quality-of-life measures

      →

      NCT01079832 · Registry condition search · Scope: unclear

      Stereotactic Radiosurgery Using CyberKnife in Treating Women With Advanced or Recurrent Gynecological Malignancies

      5 outcome links · 1 safety-group records · 1 quality-of-life measures

      →

      NCT01583686 · Registry condition search · Scope: unclear

      CAR T Cell Receptor Immunotherapy Targeting Mesothelin for Patients With Metastatic Cancer

      2 outcome links · 5 safety-group records · 0 quality-of-life measures

      →

      NCT01585428 · Registry condition search · Scope: unclear

      Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Human Papillomavirus-Associated Cancers

      2 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT01631552 · Source cited / selected · Scope: unclear

      Study of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial Cancer

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT02001623 · Source cited / selected · Scope: unclear

      Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors

      6 outcome links · 15 safety-group records · 0 quality-of-life measures

      →

      NCT02466971 · Registry condition search · Scope: unclear

      Testing the Addition of a New Anti-Cancer Drug, Triapine, to the Usual Chemotherapy Treatment (Cisplatin) During Radiation Therapy for Advanced-stage Cervical and Vaginal Cancers

      6 outcome links · 2 safety-group records · 0 quality-of-life measures

      →

      NCT02552121 · Source cited / selected · Scope: unclear

      Tisotumab Vedotin (HuMax®-TF-ADC) Safety Study in Patients With Solid Tumors

      6 outcome links · 8 safety-group records · 0 quality-of-life measures

      →

      NCT03260023 · Registry condition search · Scope: unclear

      Phase Ib/II of TG4001 and Avelumab in HPV16 Positive R/M Cancers

      6 outcome links · 7 safety-group records · 0 quality-of-life measures

      →

      NCT03438396 · Source cited / selected · Scope: unclear

      A Trial of Tisotumab Vedotin in Cervical Cancer

      6 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT03439085 · Registry condition search · Scope: unclear

      DNA Plasmid-encoding Interleukin-12/HPV DNA Plasmids Therapeutic Vaccine INO-3112 and Durvalumab in Treating Patients With Recurrent or Metastatic Human Papillomavirus Associated C

      4 outcome links · 1 safety-group records · 0 quality-of-life measures

      →

      NCT03635567 · Source cited / selected · Scope: unclear

      Efficacy and Safety Study of First-line Treatment With Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy in Women With Persistent, Recurrent, or Metastatic

      6 outcome links · 3 safety-group records · 1 quality-of-life measures

      →

      NCT04234113 · Registry condition search · Scope: unclear

      Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors

      6 outcome links · 17 safety-group records · 0 quality-of-life measures

      →

      NCT04697628 · Source cited / selected · Scope: unclear

      Tisotumab Vedotin vs Chemotherapy in Recurrent or Metastatic Cervical Cancer

      6 outcome links · 2 safety-group records · 4 quality-of-life measures

      →

      NCT05012397 · Registry condition search · Scope: unclear

      Milademetan in Advanced/Metastatic Solid Tumors

      5 outcome links · 1 safety-group records · 0 quality-of-life measures

      →
      Source relationships and population-mapping limitations
      bindings
        mappings

          Download this complete draft source relationship record →

          Preserved source evidence · Not medical advice