Biospecimen Collection (NCT06930352)
Biospecimen Collection trial for Acute Myeloid Leukemia (NCT06930352). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with untreated acute myeloid leukemia carrying NPM1 mutations, KMT2A rearrangements, or other mutations shown to be sensitive to menin inhibition, who cannot receive standard induction or decline it.
The idea: daily oral ziftomenib blocks the menin pathway involved in leukemia-cell growth. Treatment continues for up to 24 cycles if tolerated. Blood and marrow tests track response; researchers assess remission after six cycles. Other treatment may lower white-cell counts.
This phase 2 study plans 70 patients. Uma Borate leads at Ohio State in Columbus, the sole recruiting US site.
Public record; not medical advice.
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