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Coriolus Versicolor Extract (NCT06450873)

Turkey Tail Mushroom for Treating Post-Menopausal Women With HER2-Negative ER-Positive Breast Cancer Undergoing Surgery: a one-minute explainerNCT064508731 min

Coriolus Versicolor Extract trial for Estrogen Receptor-Positive Breast Carcinoma (NCT06450873). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for postmenopausal adult women with newly diagnosed ER-positive, HER2-negative breast cancer scheduled for surgery. Tumor Ki-67 must be at least 10%, with a lesion larger than five millimeters. Metastatic disease is excluded.

The idea: take turkey-tail mushroom extract twice daily for 20–42 days before surgery. It may affect immune activity, but its precise mechanism is unknown. Researchers compare the Ki-67 growth marker before and after treatment and assess side effects.

This phase 2 study plans 40 patients. Brenda Ernst leads at Mayo Clinic in Scottsdale, the sole recruiting US site.

Public record; not medical advice.

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