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Valganciclovir (NCT07383649)

Trial to Study Anti- HCMV Therapy in Breast Cancer Patients With Progressive Intracranial Metastases and CMV Infection: a one-minute explainerNCT073836491 min

Valganciclovir trial for Brain Cancer Metastatic (NCT07383649). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for English-speaking adults over 18 with breast cancer, progressive brain metastases, and positive CMV blood testing. At least one progressive brain lesion must remain untreated by radiation.

The idea: valganciclovir blocks viral DNA replication. Researchers test whether adding this antiviral to standard cancer care affects brain-tumor response. Oral treatment is twice daily for two weeks, then a lower dose for four weeks. Scans, blood tests, and thinking tests track response and safety.

This phase 2 study plans 28 patients. Akshjot Puri leads at Houston Methodist, the sole recruiting US site.

Public record; not medical advice.

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