TriangleRadiation therapy (NCT06702033)
Radiation therapy trial for HPV-Related Oropharynx Squamous Cell Carcinoma (NCT06702033). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with HPV-related stage I–II oropharyngeal squamous-cell cancer or an HPV-related neck node with unknown primary, planning transoral surgery and neck dissection. T1–T2 node-negative disease is excluded.
The idea: surgical pathology guides postoperative radiation. High-risk patients receive radiation plus cisplatin. Intermediate-risk patients are randomized among two radiation-only schedules or lower-dose radiation with cisplatin. Lowest- and highest-risk patients leave the trial for standard care. Researchers measure recurrence at two years.
This phase 2 study plans 142 patients. Douglas Adkins leads at Washington University in St. Louis; three US sites recruit.
Public record; not medical advice.
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