TriangleBiopsy Procedure (NCT06649812)
Biopsy Procedure trial for High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements (NCT06649812). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with relapsed or refractory CD10-negative aggressive B-cell lymphoma, or high-grade lymphoma with MYC and BCL2 rearrangements. Prior treatment must include an anthracycline and an anti-CD20 antibody.
The idea: combine venetoclax, ibrutinib, prednisone, obinutuzumab and lenalidomide. They target cancer-cell survival, growth signals and immune responses. Treatment lasts up to six 21-day cycles; obinutuzumab is intravenous and the other drugs are oral.
This phase 2 study plans 120 patients. The National Cancer Institute sponsors it, with 98 recruiting US sites. Only specified lymphoma subtypes qualify; primary mediastinal lymphoma is excluded.
Public record; not medical advice.
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