TriangleBiopsy Procedure (NCT03606967)
Biopsy Procedure trial for Anatomic Stage IV Breast Cancer AJCC v8 (NCT03606967). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with PD-L1-negative metastatic triple-negative breast cancer, untreated in the metastatic setting. Earlier taxane treatment requires a twelve-month disease-free interval. Tumor tissue is required.
The idea: test whether a personalized peptide vaccine improves immune recognition of cancer. Patients first receive gemcitabine and carboplatin, with alternatives for progression or intolerance. They then receive nab-paclitaxel, durvalumab and tremelimumab, randomly with or without vaccine plus poly-ICLC injections under the skin. Researchers compare progression and safety; biopsies assess immune effects.
This phase 2 study plans 86 patients. NCI sponsors twenty-four recruiting US sites.
Public record; not medical advice.
Already in a trial?
It turns into a project to manage: visits, scans, labs, side effects and paperwork. Triangle keeps it organized in one place for you or for whoever's helping.
Organize my trial7-day free trial, then $9 a month. Cancel anytime.