TriangleBiopsy Procedure (NCT07423585)
Biopsy Procedure trial for Extensive Stage Lung Small Cell Carcinoma (NCT07423585). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with extensive-stage small-cell lung cancer starting first-line treatment. Selected patients with limited-stage recurrence over six months after chemoradiation may qualify.
The idea: tarlatamab links DLL3 on tumor cells to CD3 on T cells, directing immune attack. Infusions occur weekly for three weeks, then every two weeks. A four-week scan checks for rapid progression; those patients switch to platinum chemotherapy and checkpoint immunotherapy. Researchers assess six-month progression-free survival and safety.
This phase 2 study plans 39 patients. Asrar AlAhmadi leads at Ohio State, Columbus, the sole recruiting US site.
Public record; not medical advice.
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