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AU-011 (NCT06643884)

Suprachoroidal Administration in Subjects With Metastases to the Choroid: a one-minute explainerNCT066438841 min

AU-011 trial for Eye Cancer (NCT06643884). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults whose solid tumor has spread to the eye’s choroid. At least one lesion must be present in the study eye. Patients must not plan to change or add systemic cancer treatment during study treatment.

The idea: inject belzupacap sarotalocan into the suprachoroidal space, then activate its light-sensitive payload with a laser to damage tumor cells. Groups test doses and one or two cycles. Some participants enter observation without treatment. Researchers measure tumor size and safety.

This phase 2 study plans 24 patients. Aura sponsors eight recruiting US sites.

Public record; not medical advice.

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