TriangleLinear accelerator-based… (NCT07132190)
Linear accelerator-based stereotactic radiation for brain metastases using 0mm or 1mm PTV trial for Brain Metastases, Adult (NCT07132190). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with brain metastases from solid cancers that are rapidly growing or near specified sources of swelling or displacement. MRI and gadolinium must be suitable.
The idea: update the radiation plan using MRI on treatment day, then deliver focused radiation. Random assignment compares no added margin with a one-millimeter margin. Planning may repeat during treatment. Researchers assess tumor movement beyond the original plan, local recurrence and radiation injury.
This phase 2 study plans 60 patients. Brigham and Women’s/Dana-Farber leads it in Boston, the single recruiting US site.
Public record; not medical advice.
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