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Biospecimen Collection (NCT06918132)

Resectable lung cancer: cemiplimab and fianlimab before surgery: a one-minute explainerNCT069181321 min

Biospecimen Collection trial for Lung Non-Small Cell Carcinoma (NCT06918132). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults with removable stage IB–IIIB (N2) non-small-cell lung cancer, PD-L1 of at least 1%, and no targetable EGFR/ALK/ROS1 alteration. Prior systemic therapy or radiation for this cancer excludes entry.

The idea: give cemiplimab and fianlimab infusions every three weeks for up to three cycles before planned surgery. They block PD-1 and LAG-3, proteins that limit immune-cell activity, aiming to restore an attack on cancer. Researchers examine tumor response and safety.

This phase 2 study plans 60 patients. Kaushal Parikh leads at Mayo Clinic, with two recruiting US sites.

Public record; not medical advice.

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