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Radiation Therapy (NCT06305715)

Radiation Prior to TKI to Delay Progression in Advanced Driver-Mutated Non-small Cell Lung Cancers (RadiaNCe Lung X): a one-minute explainerNCT063057151 min

Radiation Therapy trial for Non Small Cell Lung Cancer (NCT06305715). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults with advanced non-small-cell lung cancer and a primary lung tumor. Disease may be metastatic or stage IIIB/C unsuitable for definitive combined treatment. Previous targeted therapy is excluded; up to two chemotherapy cycles are allowed.

The idea: irradiate the primary lung tumor first. Patients with an actionable driver mutation then receive a matching tyrosine-kinase inhibitor, a kinase-blocking medicine. Patients without a qualifying mutation leave the study. Researchers assess progression-free survival.

This phase 2 study plans 34 patients. Jonathan Thompson leads in Milwaukee, the sole recruiting US site.

Public record; not medical advice.

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