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Stereotactic Body Radiation Therapy (NCT06369246)

PRORAD-5 PROstate RADiation in 5 Fractions: Phase II Five Fraction Radiotherapy for Patients With Advanced Prostate Cancer.: a one-minute explainerNCT063692461 min

Stereotactic Body Radiation Therapy trial for Advanced Prostate Cancer (NCT06369246). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults with prostate adenocarcinoma, stage cT1c–T3a and Grade Group 2–5, without involved nodes on conventional imaging. Grade Group 2 requires additional unfavorable features.

The idea: pelvic lymph-node radiation is delivered in five sessions over two weeks. Researchers assess bowel and urinary side effects, quality of life, and later spread. Prior prostate removal, cryosurgery, HIFU, or overlapping radiation excludes participation. Hormone treatment can be allowed. Distant disease requires individual assessment.

This phase 2 study plans 100 patients. Comron Hassanzadeh leads at MD Anderson in Houston, the sole recruiting US site.

Public record; not medical advice.

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