TrianglePre-radiation temozolomide. (NCT07439172)
Pre-radiation temozolomide. trial for High Grade Gliomas (NCT07439172). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults aged 18–80 with newly diagnosed high-grade glioma and measurable, contrast-enhancing tumor remaining after surgery. Patients must not need urgent radiation or chemotherapy and take oral medicine.
The idea: give two temozolomide cycles before radiation to assess drug response without radiation-related MRI changes. Temozolomide damages DNA processes needed for tumor-cell replication. Patients take 200 milligrams per square meter on days one to five of each 28-day cycle. Researchers compare postoperative and pre-radiation MRI findings.
This phase 2 study plans 70 patients. Cooper Health sponsors its recruiting Camden site.
Public record; not medical advice.
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