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Biospecimen Collection (NCT07685717)

Pirtobrutinib for the Treatment of Elderly Patients With Chronic Lymphocytic Leukemia: a one-minute explainerNCT076857171 min

Biospecimen Collection trial for Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (NCT07685717). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for people aged seventy-five or older with previously untreated chronic lymphocytic leukemia or small lymphocytic lymphoma that meets criteria for starting treatment.

The idea: test daily pirtobrutinib tablets in repeating four-week cycles. Pirtobrutinib blocks BTK, a protein involved in cancer-cell growth signaling. Researchers measure response and treatment discontinuation after twelve cycles, alongside safety, daily functioning and quality of life. CT scans, blood tests and bone-marrow sampling track treatment. There is no comparison drug group.

This phase 2 study plans 50 patients. Jennifer Woyach leads Ohio State's recruiting Columbus site.

Public record; not medical advice.

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