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Fecal Microbiota Transplantation (NCT06218602)

Pilot Trial of Fecal Microbiota Transplantation for Lymphoma Patients Receiving Axicabtagene Ciloleucel Therapy.: a one-minute explainerNCT062186021 min

Fecal Microbiota Transplantation trial for Lymphoma (NCT06218602). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults with B-cell lymphoma scheduled for axicabtagene ciloleucel who received at least two days of specified antibiotics within 180 days before the infusion.

The idea: fecal microbiota transplantation aims to restore gut bacteria disrupted by antibiotics. Researchers compare chemotherapy and CAR T treatment with or without this treatment. They assess toxicity and cancer response. The transplant arm lists oral capsules and colonoscopy; the study team must confirm delivery details.

This phase 2 study plans 40 patients. Neeraj Saini leads at MD Anderson in Houston, the sole recruiting US site.

Public record; not medical advice.

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