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Proton Radiotherapy (NCT01766297)

Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer: a one-minute explainerNCT017662971 min

Proton Radiotherapy trial for Breast Cancer (NCT01766297). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for women aged fifty or older with ER-positive, node-negative ductal breast cancer or DCIS after lumpectomy with clear margins. Tumors must meet size limits; lobular cancer and known BRCA mutations are excluded.

The idea: use ten proton-radiation treatments around the original tumor site instead of irradiating the whole breast. The aim is to preserve cancer control while limiting radiation to nearby healthy tissue. Researchers track same-breast recurrence and treatment effects in one group.

This phase 2 study plans 132 patients. Proton Collaborative Group sponsors nine recruiting US sites.

Public record; not medical advice.

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