TriangleBiospecimen Collection (NCT06745076)
Biospecimen Collection trial for Advanced Hodgkin Lymphoma (NCT06745076). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with untreated stage III or IV classical Hodgkin lymphoma who can receive six cycles of combination treatment. Active central nervous system lymphoma is excluded.
The idea: use blood tumor-DNA testing after two cycles to guide chemotherapy reduction. Everyone starts nivolumab, which releases an immune brake, plus doxorubicin, vinblastine and dacarbazine. DNA-negative patients receive four chemotherapy cycles, then two nivolumab-only cycles; DNA-positive patients receive all four drugs for six cycles.
This phase 2 study plans 125 patients. University of Washington sponsors it; six US sites are recruiting.
Public record; not medical advice.
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