TriangleBiospecimen Collection (NCT07557056)
Biospecimen Collection trial for Chronic Lymphocytic Leukemia (NCT07557056). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with previously untreated chronic lymphocytic leukemia or small lymphocytic lymphoma that meets criteria for treatment. Richter transformation and active brain or spinal involvement are excluded.
The idea: block BTK growth signaling with nemtabrutinib and the BCL-2 survival protein with venetoclax. Patients take nemtabrutinib daily, adding daily venetoclax from cycle three. Treatment lasts up to fourteen 28-day cycles. Researchers test blood for residual leukemia and monitor safety. Scans and bone-marrow sampling are required.
This phase 2 study plans 25 patients. Jennifer Woyach leads at Ohio State’s recruiting Columbus site.
Public record; not medical advice.
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