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Microboost SBRT (NCT07644598)

MRI-based Focal Intraprostatic Simultaneous Integrated Boost (SIB) Intensification With De-escalated Adaptive-risk SBRT for Patients With Low to Intermediate Risk Prostate Cancer: a one-minute explainerNCT076445981 min

Microboost SBRT trial for Prostate Cancer (NCT07644598). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adult men with localized low- or intermediate-risk prostate cancer and up to four MRI-visible lesions. Prior prostatectomy, pelvic radiation, or androgen-deprivation treatment is excluded.

The idea: radiation gives visible lesions a 45-gray boost across five sessions while the whole gland receives 30 or 35 gray. Disease grade outside the boosted area determines the group. Treatment occurs on alternate days. Fiducial markers are required; a rectal spacer is optional. Researchers monitor urinary toxicity.

This phase 2 study plans 58 patients. Georgetown sponsors the sole recruiting US site in Washington, DC.

Public record; not medical advice.

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