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Biospecimen Collection (NCT06442475)

Low Dose Mosunetuzumab for the Treatment of Patients With Indolent B-Cell Lymphoma: a one-minute explainerNCT064424751 min

Biospecimen Collection trial for Ann Arbor Stage II Follicular Lymphoma (NCT06442475). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults with untreated stage II–IV follicular lymphoma, grades 1–3A, or marginal-zone lymphoma. Tumor burden must be low, without B symptoms or organ-compression risk.

The idea: mosunetuzumab links T cells to CD20-bearing lymphoma cells to direct an immune response. Patients receive four intravenous treatments, one week apart, in this low-dose study. Researchers measure complete or partial responses by week 13. Blood tests and PET/CT scans monitor treatment.

This phase 2 study plans 20 patients. Ajay Gopal leads at Fred Hutch/UW in Seattle, the sole recruiting US site.

Public record; not medical advice.

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