TriangleStandard of care chemotherapy (NCT07222657)
Standard of care chemotherapy trial for Esophageal Adenocarcinoma (NCT07222657). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with locally advanced esophageal adenocarcinoma without distant metastases, planning FLOT chemotherapy, with or without durvalumab.
The idea: liquid nitrogen spray freezes tumor tissue through an endoscope, causing cell damage. Patients are randomized to chemotherapy with or without two cryotherapy sessions, one to two weeks apart. Both groups receive systemic treatment. Researchers compare complete responses on scans and tissue assessment. Control-group endoscopy may still be needed for symptoms.
This phase 2 study plans 40 patients. Tilak Shah leads at Cleveland Clinic Florida in Weston, one recruiting US site.
Public record; not medical advice.
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