TriangleBiopsy Procedure (NCT07226544)
Biopsy Procedure trial for Localized Clear Cell Renal Cell Carcinoma (NCT07226544). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with high-risk, localized clear-cell kidney cancer that can be removed surgically. Prior systemic kidney-cancer treatment and metastatic disease are excluded.
The idea: give ivonescimab before surgery to study tumor response. This antibody acts through immune defenses and blocks new blood-vessel growth. Patients receive four intravenous treatments, three weeks apart, then kidney surgery four to ten weeks later. A pretreatment biopsy is required.
This phase 2 study plans 31 patients. Wesley Yip leads at City of Hope in Duarte, the sole recruiting US site.
Public record; not medical advice.
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