TriangleBiopsy Procedure (NCT07094685)
Biopsy Procedure trial for Advanced Head and Neck Squamous Cell Carcinoma (NCT07094685). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with resectable stage II–IV mucosal head-and-neck squamous cancer and PD-L1 combined positive score of at least one. Prior radiation for this cancer or same-side neck dissection excludes participation.
The idea: ivonescimab blocks the PD1 immune brake and VEGF signals involved in blood-vessel growth. Patients receive up to three infusions, three weeks apart, then surgery four to eight weeks after the last dose. Researchers assess tissue response.
This phase 2 study plans 28 patients. Paul Swiecicki leads at University of Michigan, Ann Arbor, the sole recruiting US site.
Public record; not medical advice.
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