TriangleCisplatin (NCT07392580)
Cisplatin trial for Laryngeal Squamous Cell Carcinoma (NCT07392580). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with laryngeal squamous-cell cancer that returned after radiation and requires surgery.
The idea: cisplatin damages cancer-cell DNA and is injected directly into the tumor with epinephrine. Patients receive three weekly injections under local anesthesia, then surgery. Early disease is removed endoscopically; advanced disease requires removal of the larynx. A biopsy is taken with the first injection. Researchers examine removed tissue to measure response and monitor side effects.
This phase 2 study plans 20 patients. David Rosow leads at the University of Miami, the sole recruiting US site.
Public record; not medical advice.
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