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Biospecimen Collection (NCT06518057)

Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer: a one-minute explainerNCT065180571 min

Biospecimen Collection trial for Anatomic Stage IV Breast Cancer AJCC v8 (NCT06518057). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for adults with breast or non-small-cell lung cancer that has spread to the membranes around the brain or spinal cord, diagnosed by imaging or spinal-fluid testing.

The idea: proton or photon radiation treats the brain and spine while limiting radiation to the hippocampus. Treatment occurs on ten weekdays over about two weeks. Researchers measure cancer control in the central nervous system and safety. Spinal-fluid collection is optional at the physician's discretion.

This phase 2 study plans 22 patients. Lia Halasz leads; Seattle and New York have recruiting sites.

Public record; not medical advice.

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