TriangleBiospecimen Collection (NCT06834373)
Biospecimen Collection trial for Large B-Cell Lymphoma With IRF4 Rearrangement (NCT06834373). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with specified aggressive B-cell lymphomas that relapsed or resisted one or two treatment lines. Patients must be potential CAR-T candidates. Richter transformation is excluded.
The idea: oral golcadomide promotes breakdown of proteins involved in cell growth and immune regulation; infused rituximab targets CD20. Researchers test disease control while preparing for CAR-T. Treatment and cell-collection timing depend on CAR-T eligibility; CAR-T is not guaranteed.
This phase 2 study plans 41 patients. Claire Tiger leads the Mayo Clinic study, with seven recruiting US sites. Researchers assess control after two cycles.
Public record; not medical advice.
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