TriangleGenomically Guided Radiation Therapy (NCT05528133)
Genomically Guided Radiation Therapy trial for Triple Negative Breast Cancer (NCT05528133). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with nonmetastatic breast cancer after lumpectomy and lymph-node assessment, with clear surgical margins. Tumors must be HER2-negative, with estrogen and progesterone receptor staining below ten percent. Genomic testing requires tumor tissue.
The idea: use a gene-based radiosensitivity score to guide whole-breast radiation. Treatment is given five days weekly. Some patients receive an additional boost to the surgery cavity; lymph-node radiation depends on need. Researchers measure cancer control in the treated breast at three years.
This phase 2 study plans 86 patients. Kamran Ahmed leads two recruiting Florida sites.
Public record; not medical advice.
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