TriangleApalutamide 60mg Tab (NCT04812366)
Apalutamide 60mg Tab trial for Prostate Cancer (NCT04812366). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adult men with high-risk prostate cancer eligible for prostate removal. Limited spread found only on PSMA imaging may be allowed.
The idea: tumor gene testing guides preoperative treatment. Everyone starts hormone suppression with apalutamide, which blocks androgen receptors. Later treatment depends on the gene group and may involve randomization. Some groups receive chemotherapy or targeted drugs. The atezolizumab and tazemetostat groups are closed. Researchers examine the removed tissue for cancer.
This phase 2 study plans 315 patients. Martin Gleave leads for University of British Columbia; five US sites recruit.
Public record; not medical advice.
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