TriangleFunctional Precision Oncology (NCT05464082)
Functional Precision Oncology trial for Breast Cancer Recurrent (NCT05464082). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with untreated stage I–III triple-negative or hormone-receptor-low, HER2-negative breast cancer being considered for preoperative chemotherapy. Tumor collection must be safe.
The idea: researchers grow tumor models in mice and as organoids, then test drugs on those models. If distant recurrence occurs, results may inform second-line treatment after metastatic therapy. Doctors choose treatment and need not follow the recommendations. The study also examines whether model growth predicts recurrence.
This phase 2 study plans 80 patients. Christos Vaklavas leads at Huntsman in Salt Lake City, the sole recruiting US site.
Public record; not medical advice.
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