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18F-DCFPyL (NCT05616650)

Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor: a one-minute explainerNCT056166501 min

18F-DCFPyL trial for Prostatic Neoplasms (NCT05616650). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

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This trial is for men aged 18–120 with untreated, low- or intermediate-risk prostate cancer. MRI, PSMA PET and targeted biopsy must identify one tumor focus. Pelvic or distant spread and planned hormone therapy or chemotherapy are excluded.

The idea: direct radiation at the tumor focus, guided by imaging and implanted gold markers. SBRT delivers 26 Gy across two sessions, no more than eight days apart. Scans, PSA tests and a two-year biopsy assess response.

This phase 2 study plans 42 patients. Deborah Citrin leads at NIH in Bethesda, the sole recruiting US site.

Public record; not medical advice.

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