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Biospecimen Collection (NCT07460752)

Evaluation of Alternative Site Goserelin Acetate Injection for Ovarian Function Suppression (OFS) in Local and Locally Advanced Premenopausal Hormone Receptor Positive Breast Cancer Patients: a one-minute explainerNCT074607521 min

Biospecimen Collection trial for Anatomic Stage I Breast Cancer AJCC v8 (NCT07460752). This is a short film with English narration. The transcript is on this page, and the written brief is separate.

What the film says

Read the transcript

This trial is for premenopausal women aged eighteen to forty-nine with stage one to three estrogen-receptor-positive breast cancer in remission. They must already use monthly goserelin plus tamoxifen or an aromatase inhibitor for six months.

The idea: test goserelin injections under the skin of the upper buttock. Continued goserelin lowers estrogen production. After a six-cycle abdominal-injection lead-in, eligible patients receive buttock injections every four or twelve weeks. Blood tests check whether ovarian suppression continues.

This phase 2 study plans 98 patients. Karthik Giridhar leads Mayo Clinic's recruiting Rochester site.

Public record; not medical advice.

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