TriangleComputed Tomography (NCT07178301)
Computed Tomography trial for Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 (NCT07178301). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with untreated HPV-related oropharyngeal squamous cancer, stage I–II, with lymph-node involvement and no distant spread. HPV in-situ hybridization confirmation is required.
The idea: ENLIGHT reduces radiation to uninvolved neck nodes while retaining the standard tumor dose. Patients receive seventy gray to gross tumor and thirty gray to the elective neck, over thirty-five weekday treatments in seven weeks. Chemotherapy is optional under usual care. Researchers track recurrence, survival, and side effects.
This phase 2 study plans 100 patients. Laila Gharzai leads at Northwestern, Chicago; two US sites recruit.
Public record; not medical advice.
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