Autologous Hematopoietic Stem Cell… (NCT07365306)
Autologous Hematopoietic Stem Cell Transplantation trial for Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified (NCT07365306). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with selected CD20-positive large B-cell lymphomas that returned or resisted treatment, who qualify for high-dose chemotherapy and autologous stem-cell transplantation. Prior CAR T treatment affects eligibility.
The idea: epcoritamab links T cells to CD20-bearing lymphoma cells. Injections under the skin accompany rituximab, gemcitabine, and oxaliplatin. Responders may proceed to transplant and further epcoritamab; responders unable to undergo transplant can also receive consolidation. Researchers measure complete responses.
This phase 2 study plans 43 patients. Geoffrey Shouse leads at City of Hope in Duarte, the sole recruiting US site.
Public record; not medical advice.
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