TriangleBiospecimen Collection (NCT06723457)
Biospecimen Collection trial for Recurrent B-Cell Non-Hodgkin Lymphoma (NCT06723457). This is a short film with English narration. The transcript is on this page, and the written brief is separate.
What the film says
Read the transcript
This trial is for adults with specified immunodeficiency-related large B-cell lymphomas or polymorphic B-cell disorders after treatment failure. Patients must be ineligible for CAR-T therapy; prior-treatment requirements vary by cohort.
The idea: epcoritamab directs T cells toward lymphoma cells, while lenalidomide enhances immune activity. Patients receive epcoritamab under the skin and oral lenalidomide for up to twelve months. Epcoritamab changes from weekly to monthly dosing after three cycles. Researchers measure complete response and safety.
This phase 2 study plans 34 patients. Reem Karmali leads at Northwestern, Chicago, the sole recruiting US site.
Public record; not medical advice.
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